General Adult Diabetic Sick Day Instructions (at home) |
|
Hospital admission
Hospitalized patients frequently develop hyperglycemia and metabolic changes arising from the stress response that accompanies medical procedures and acute illnesses. Plummer, Finnis, et al. (2016) identified stress induced hyperglycemia in 17% of ICU patients without diabetes.
Myocardial infarction, stroke , influenza, infection, surgery, medications, injuries, or any significant stress can increase blood glucose in diabetics and non-diabetics. The body responds to stress and illness by increasing the secretion of glucocorticoids, norepinephrine, epinephrine, growth hormone and inflammatory mediators: cytokines, tumor necrosis factor, Interleukin-2. The action of these substances cause elevated plasma glucose by increasing hepatic glucose output (glycogenolysis & gluconeogenesis) and decreasing insulin mediated uptake by peripheral tissue.
Diabetics have a decreased ability to cope with illness or stress related hyperglycemia. The absence of insulin or its effects inhibit the body's ability to store excess glucose and suppress the catabolic effects of glucagon. Diabetics may lack the ability to regain euglycemia even when stress is short-term, as may occur during strenous physical exercise. This fact necessitates constant vigilance and frequent blood glucose monitoring.
ADA 2023 Recommendations For Diabetes Care in the Hospital (excerpts
2023 ADA GLYCEMIC TARGETS IN HOSPITALIZED Adults
- Insulin therapy should be initiated for treatment of verified persistent hyperglycemia starting at a threshold of ≥180 mg/dL (10 mmol/L). Once insulin therapy is started, a glucose range of 140–180 mg/dL (7.8–10 mmol/L) is recommended for the majority of critically ill and non-critically ill patients."
- Non-critically ill patient BG goals: "There is no clear evidence for specific blood glucose goals. If treated with insulin, the premeal blood glucose targets generally <140 mg/dL (7.8 mmol/L) with random blood glucose <180 mg/dL (10.0 mmol/L) are reasonable, provided these targets can be safely achieved."
- More stringent goals, such as 110–140 mg/dL (6.1–7.8 mmol/L), or 100-180 mg/dL (5.6-10.0 mmol/L) may be appropriate for selected patients if they can be achieved without significant hypoglycemia.
- Hypoglycemia treatment should prevent a blood glucose value of <70 mg/dL or (3.9 mmol/L)
Instant Feedback:
When sick, diabetics should? (Best answer)
References
Diabetes care. Standards of Care in Diabetes. American Diabetes Association. (2023). https://diabetesjournals.org/care/issue/46/Supplement_1
Moghissi, E.S., Korytkowski, M.T., DiNardo, M. , et al. (2009). American Association of Clinical Endocrinologists and American Diabetes Association consensus statement on inpatient glycemic control. Diabetes Care. 32, 1119–1131.
Plummer, M. P., Finnis, M. E., Phillips, L. K., Kar, P., Bihari, S., Biradar, V., Moodie, S., Horowitz, M., Shaw, J. E., & Deane, A. M. (2016). Stress Induced Hyperglycemia and the Subsequent Risk of Type 2 Diabetes in Survivors of Critical Illness. PloS one, 11(11), e0165923. https://doi.org/10.1371/journal.pone.0165923
Vedantam, D., Poman, D. S., Motwani, L., Asif, N., Patel, A., & Anne, K. K. (2022). Stress-Induced Hyperglycemia: Consequences and Management. Cureus, 14(7), e26714. https://doi.org/10.7759/cureus.26714