Prognosis
This index analyzes and
calculates four main factors:
1. Age
2. Size of DCIS involvement
3. Grade of the DCIS
4. Width of the margins
Each of these four factors is given a score of 1 (low), 2 (medium), or 3 (high), as shown in the table below. The total of the four scores is the total VNPI score. The lowest possible score is 4 (4 times 1) and the highest is 12 (4 times 3). The higher the score, the more likely it is that the DCIS will recur.
Score |
1 |
2 |
3 |
Size (mm) |
less
than or equal to 15 |
16
- 40 |
more
than or equal to
41 |
Margin width (mm)/td |
more
than or equal to
10 |
1
- 9 |
less
than or equal to 1 |
Pathologic classification |
Non-high
grade without necrosis (nuclear grades 1 or 2) |
Non-high
grade with necrosis (nuclear grades 1 or 2) |
High
grade with or without necrosis (nuclear grade 3) |
Age (yrs) |
>60 |
40
- 60 |
<40 |
Table from "The University
of Southern California/Van Nuys prognostic index for ductal carcinoma in situ
of the breast" by Melvin J. Silverstein, American Journal of Surgery, Volume
186, Issue 4, October 2003.
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